proteasome相关论文
Shikonin Promotes Skin Cell Proliferation and Inhibits Nuclear Factor-κB Translocation via Proteasom
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泛素-蛋白酶体系统(ubiquitin-proteasome system, UPS)是体内蛋白降解的重要通路.许多证据表明帕金森病(Parkinson disease, PD)......
近二十年来,有关泛素的研究得到了飞速的发展,泛素化是细胞体内一种非常重要的蛋白质翻译后修饰方式,泛素-蛋白酶体途径(ubiquitin......
The 26S proteasome at the center of the ubiquitinproteasome system (UPS) is essential for virtually all cellular process......
化疗在肿瘤治疗中具有重要地位，其最主要的障碍之一即肿瘤细胞对药物耐受性的出现，前期的蛋白质组学研究中已经发现，人慢性髓细胞白血......
泛素化是蛋白质翻译后重要修饰之一,是蛋白质降解信号,被泛素化修饰的蛋白质被蛋白酶识别从而被降解.近年来,人们通过对泛素化-蛋......
Background Hepatitis B virus (HBV) x protein (HBx) in HepG2 cells causes a moderate decrease in proteolysis activity of ......
Shikonin Promotes Skin Cell Proliferation and Inhibits Nuclear Factor-κB Translocation via Proteasom
Background:Shikonin is a major active chemical component extracted from Lithospermi Radix,an effective traditional herb ......
The VCP-Ufd1-Npl4 complex regulates proteasomal processing within cells by delivering ubiquitinated proteins to the prot......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
帕金森病(Parkinsons disease,PD)是一种中老年常见的进行性神经系统变性疾病,其病理特征为黑质致密部多巴胺能神经元选择性、进行......
目的 探讨20S蛋白酶体在晚期胃癌患者外周血白细胞中活性变化及其临床意义.方法 分离80例晚期胃癌患者外周血白细胞,应用20S蛋白酶......
Protein degradation through the ubiquitin-proteasome system is the major pathway of non-lysosomal proteolysis of intrace......
In the processing and presentation of antigenic peptides bound by the major histocompatibility complex (MHC) class I mol......
In order to study the effects of ubiquitin-proteasome pathway (UPP) on mouse oocyte meiosis and cleavage, oocytes underg......
11-Oxo-10,11-dihydroxy-5H-indolo[3,2,b]quinoline7-carboxylic acid was obtained specifically by polyphosphorous acid cata......
目的 探讨抑制蛋白酶体功能对人胶质瘤SHG-44细胞内自噬途径的激活作用.方法 采用5.0μmol/L蛋白酶体特异性抑制剂MG-132抑制人胶......
Proteasome activity reduction is all important pathological phenomenon,resulting in proteins aggregation and neuronal de......
目的 研究蛋白酶体和自噬两条主要蛋白质降解途径在细胞体外及糖尿病肾病(DN)模型大鼠体内中的变化.方法 原代培养SD大鼠肾小球系......
